Sorafenib

Brand name: Nexavar

Description

Chemotherapy

The drug can be prescribed for locally advanced or metastatic differentiated thyroid cancer, which has not previously responded to radioactive iodine therapy

Brands: Nexavar

Availability: Prescription needed

Pregnancy: Consult a doctor

Alcohol: Not detected with light alcohol consumption

Side Effects: Hearing Loss, Dry Skin And Hair, Depressed Mood

Interactions: Levothyroxine, Fluoxetine, Ondansetron

For informational purposes only. Consult your local medical authority for advice.

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What side effects may I notice from Nexavar?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using sorafenib and call your doctor at once if you have:

• mouth sores;

• blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;

• heavy menstrual periods, easy bruising, unusual bleeding, or any bleeding that will not stop;

• pale skin, feeling light-headed, rapid heart rate, trouble concentrating;

• dry cough, wheezing;

• chest pain and severe dizziness, fainting, sweating, swelling, rapid weight gain, feeling short of breath (even with mild exertion);

• rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;

• upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• sudden weight loss, increased appetite, trouble sleeping, increased bowel movements, feeling hot, feeling nervous or anxious, swelling in your neck (goiter);

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, confusion, uneven heartbeats, seizure); or

• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

• tired feeling;

• vomiting, diarrhea, mild stomach pain;

• mild itching or rash; or

• weight loss, thinning hair.

This is not a complete list of side effects and others may occur.

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